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Hi,
Is there any function to round up a floating point variable within the hoc code?

thanks and regards

Sir,

I wanted your opinion on the following. If I want to calculate the depletion of ca in a fixed extracellular volume and i have inserted a L type Ca channel and the cdp mechanism in the section, then, can i proceed in a way similar to that outlined in the thread on Extracellular K accumulation?

Dear Sir, I was experimenting with the model for potassium accumulation which had been initially discussed in this post. The one in which accumulation is implemented in the ECS alongwith corresponding depletion in ICS. You had helped me out with the framing of the equations controlling ki and ko and...

Dear Sir, as always, I am STUCK again.Let me tell you what i did to test the model First I implemented Accumulation in ECS, depletion in ICS and diffusion to a constant volume sink using the relations given below ko'=(1e4)*4*ik/(rho*diam*FARADAY)+(ks-ko)/taus ks'=(ko-ks)/taus ki=kx-ko*rho-ks*rhosnk ...

Hi, I am working on a ca accumulation mechanism which i want to use in modeling pyramidal neurons found in v1 area of cat visual cortex. I would be grateful if someone can tell me or point me in the right direction as to the approximate levels of intracellular calcium concentration that would lead t...

Thank you sir, Actually, even I by myself had employed similar suggestions as given by you but was not sure whether I was doing it right. Your post has reassured me that I was on the right track. However the behavior is still not as I desired, so I am trying to work out another way of doing it. In c...

Hi,

I managed to work it out myself!

Thanks anyway

Sir,

Can you please elaborate a little on how to use the record() method.

Is it possible to use this method to calculate the number of spikes generated in distinct time periods and not just the total number of spikes in the entire simulation?

regards

Dear Sir, The Potassium accumulation mechanism is working as desired. Many thanks for the same. Now, moving ahead, my next step is to implement a sink which is attached to the extracellular space(ECS) and sucks out the accumulated K+ from the ECS. However the efficiency of sucking out is to be inver...

Thanks Ted,

I'll try to do it some other way

Hi, I am not sure if this falls into the realm of parellalization so I have posted this query here. I want to know whether it is possible to simultaneously simulate a group of neurons, all of which may not necessarily be connected to each other but they do share the same extracellular space. Also, t...

Dear Sir,

Thank you once again. I have started understanding NMODL a little better now, all because of you.

Dear Sir, 1. I made the necessary amendments in the kext.mod file as you had suggested. Here is the kext.mod code : Extracellular potassium ion accumulation NEURON { SUFFIX kext USEION k READ ik WRITE ko,ki RANGE fhspace } UNITS { (mV) = (millivolt) (mA) = (milliamp) FARADAY = (faraday) (coulombs) (...

Thank you sir. I really appreciate the promptness and detail, of the reply

Hi , I am trying to create a mechanism that reads the potassium current ik and computes the values of ki and ko. What i also require is that ik should also be dependent on the newly modified values of ik and ko. The model that I have in mind is a single compartment soma(with a certain initial potass...