Search found 26 matches

by ylzang
Tue Aug 20, 2019 10:40 am
Forum: Getting started
Topic: multiple pulse current clamp point process
Replies: 2
Views: 305

Re: multiple pulse current clamp point process

Thanks. works perfect!
by ylzang
Tue Aug 20, 2019 10:02 am
Forum: Getting started
Topic: multiple pulse current clamp point process
Replies: 2
Views: 305

multiple pulse current clamp point process

According to the documentation, IClamp is a single pulse current clamp point process. I need IClamp to generate several pulses (variable intervals). Is this doable without generating multiple point processes and setting each process corresponding delay time? I tried to use Netstim and then use NetCo...
by ylzang
Mon Apr 16, 2018 8:18 am
Forum: Getting started
Topic: modulus in the mod file
Replies: 3
Views: 1412

Re: modulus in the mod file

syntax error:
Illegal expression:
Illegal statement:
Illegal block at line 114 in file Isinunoisy.mod
if ((t%1000)>500) {
^
make: *** [Isinunoisy.c] Error 1

The above is the error information. However, I can use % in the terminal.
by ylzang
Thu Apr 12, 2018 12:37 am
Forum: Getting started
Topic: modulus in the mod file
Replies: 3
Views: 1412

modulus in the mod file

Hi,
I am trying to use the built-in expression % to compute the modulus in mod file. However, there are errors for the compilation of the mod files. I have tried this expression in GUI. It works perfectly. Can anybody tell me why? Thanks.
by ylzang
Tue Aug 22, 2017 8:41 am
Forum: Getting started
Topic: Suggestion for dynamic synaptic inputs
Replies: 6
Views: 9518

Re: Suggestion for dynamic synaptic inputs

once the cell receives stimulus, the presynaptic input firing rate (signal) is like a sinusoidal wave FR = sin((t-stimulus_onset)/10), when t<stimulus_onset or t>stimulus_onset+10*pi. sin((t-stimulus_onset)/10) is negative half of the time. Would you like to revise the expression for firing rate? Y...
by ylzang
Mon Aug 21, 2017 9:44 pm
Forum: Getting started
Topic: Suggestion for dynamic synaptic inputs
Replies: 6
Views: 9518

Re: Suggestion for dynamic synaptic inputs

To go any further, you will have to provide a mathematical description of the effect of a stimulus on presynaptic firing rate. It would be best if your description is based on experimental evidence. Yes, I am trying to simulate the cell spiking in vivo. It includes two stages, the resting state and...
by ylzang
Sun Aug 20, 2017 9:05 pm
Forum: Getting started
Topic: Suggestion for dynamic synaptic inputs
Replies: 6
Views: 9518

Re: Suggestion for dynamic synaptic inputs

ted wrote:What do you need help with--attaching a bunch of synapses to a model cell, or making the presynaptic firing rates change in a way that represents the effect of a stimulus?
Thanks Ted. The second one would be the question.
by ylzang
Tue Aug 15, 2017 11:07 pm
Forum: Getting started
Topic: Suggestion for dynamic synaptic inputs
Replies: 6
Views: 9518

Suggestion for dynamic synaptic inputs

I have built a cell model and now I want to do the in vivo simulations. When the animal is at resting condition, there are only spontaneous/background synaptic inputs. To make it simple, I assume there are 1000 synaptic contacts uniformly formed on the dendrite from another type of cells. At resting...
by ylzang
Thu Jan 05, 2017 7:27 pm
Forum: Other questions
Topic: calculating impedance at different frequencies
Replies: 2
Views: 4731

Re: calculating impedance at different frequencies

Impedance is calculated in the frequency domain from the Laplace transformation of the spatially discretized cable equation. As mentioned here https://www.neuron.yale.edu/phpBB/viewtopic.php?f=8&t=3515&p=14922 the second argument to the Impedance class's compute() method specifies whether voltage-d...
by ylzang
Wed Jan 04, 2017 2:40 am
Forum: Other questions
Topic: calculating impedance at different frequencies
Replies: 2
Views: 4731

calculating impedance at different frequencies

I am wondering how Neuron compute the impedance at different frequencies. I mean if I write the hoc code myself, Obviously I need to exert an input signal and then record the change of the membrane potential. For 0 HZ input impedance, it is easy to understand. What is the input signal for NEURON to ...
by ylzang
Tue Jun 14, 2016 8:54 am
Forum: Reaction-diffusion in NEURON
Topic: How to solve the calcium summation problem?
Replies: 5
Views: 10023

Re: How to solve the calcium summation problem?

I am glad to provide whatever advice I can that would help you and your advisor achieve your goals. Much of it I have already provided. However my primary obligations will consume nearly all of my effort for the next three weeks, and even after that I will not have the time to take on a new modelin...
by ylzang
Sun Jun 12, 2016 10:44 pm
Forum: Reaction-diffusion in NEURON
Topic: How to solve the calcium summation problem?
Replies: 5
Views: 10023

Re: How to solve the calcium summation problem?

The more detail that is included in a model, the more difficulty there is in selecting model parameters and getting desired results. That's why so many computational neuroscience models don't bother with ion accumulation--it is just assumed that concentrations are constant. Many modelers have used ...
by ylzang
Wed May 25, 2016 11:32 pm
Forum: Reaction-diffusion in NEURON
Topic: How to solve the calcium summation problem?
Replies: 5
Views: 10023

Re: How to solve the calcium summation problem?

Thanks for the reply. Yes, the simple calcium handling mechanism do make the problem more simple.
by ylzang
Mon May 16, 2016 4:00 am
Forum: Reaction-diffusion in NEURON
Topic: How to solve the calcium summation problem?
Replies: 5
Views: 10023

How to solve the calcium summation problem?

When using the detailed calcium handling mechanism including the buffering and diffusion, I met a problem to simulate the repetitive firing of the soma in Purkinje cell. Let's take the example of cdp model in the NEURON BOOK, there will be a long tail part for the decay of the calcium transient. For...
by ylzang
Wed Jan 06, 2016 1:45 am
Forum: Reaction-diffusion in NEURON
Topic: calcium diffusion in different shells
Replies: 8
Views: 6967

Re: calcium diffusion in different shells

Thanks for the reply. Yes, I am collaborating with other experimentalist and I will contact him to get more details. Thanks again.