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I'm trying to install NEURON on my MacBook OS X 10.10.3, following the instruction on http://www.neuron.yale.edu/neuron/download/compilestd_osx "Make" fails at step II C. Any help? $ make Making all in src Making all in lib libtool: compile: g++ -DHAVE_CONFIG_H -I. -I. -I../include -I/usr/...

Hi there, I have a detailed single neuron model and want to extract the parents and children of a section, let's say necks[0]. oc>psection() necks[0] { nseg=1 L=2.78238 Ra=180.122 dend[14] connect necks[0] (0), 0.857143 /* First segment only */ insert morphology { diam=0.18} insert capacitance { cm=...

I have a multicompartment neuron model and use SEClamp. When the pulse amplitude is below about +50mV, it is working perfectly. But when the pulse amplitude is larger than +60mV, the measured voltage as well as the electrode current become nan. I wonder whether it is a precision problem.

when I use SEClamp to perform an experiment, I usually got some small transient in the beginning of the simulation. But occasionally I got some very positive and very negative values (10 to the 4 order of magnitude bigger) at t=0 and it decays rapidly. Are they still transients? Is it possible to av...

Thanks for your patient reply. And we have further inquiries. I think we understand different things by "... what portion of that clamp current is attributable to sodium current..." I understand that in a typical experimental voltage-clamp characterization of an ion channel, the current is...

Let me clarify. We have some voltage clamp data in presence of step depolarizations and ion channel blockers. Our data are current recorded at the soma with unit Ampere. We have built a model using NEURON with topology and multiple ion channels. Next goal: reproduce the experimental result in the NE...

The current recorded by a voltage clamp attached to the soma reflects contributions from all membrane currents throughout the entire cell, subject to filtering (signal loss) due to the properties of the membrane and cytoplasm that separates the clamp electrode from any given patch of membrane. Do y...

Thanks for the detailed reply. In fact, we already have a neuron model with topology reconstructed from experimental data, and want to further compare its neuronal dynamics with physiological data. Adding only one channel and then recording the SEC i is not a good option as we want a realistic model...

Hi! I want to fit some data from voltage clamp experiments. Now I have a multi-compartment model and use VClamp(0.5) as the stimulation. Somewhere in the mod files, ik is 'assigned' ASSIGNED { ik (mA/cm2) ...} In my code, vector_current.record(&soma.ik(.5)) I got a reasonable trace of the record...

It works when 'local nil' is removed from the obfunc.
Thanks!

I have the following code in a proc for i=0, nclist.count-1 { dfile.printf("%s\t%s\n", myprecell(nclist.object(i)), nclist.object(i).postcell)} obfunc myprecell(){...} is defined in the same file, just above the proc. I get the following error message and do not know what's wrong: bad stac...

Hi there! I want to extract the connectivity of the network. I'm using an artificial cell as Poisson input sources and a usual neuron model for neurons. When printing the pre and post cells with for i=0, nclist.count-1 {dfile.printf("%s\t%s\t%s\n", nclist.object[i].precell, nclist.object[i...