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I builded a pyramidal cell with the cell builder (it's a reduced model of the cat visual cortex layer5). The public members are: public soma, BasalTrunk, basal1, basal2, ApicalTrunk, Apical1, Apical2 public Obliques public all, Basals public AMPAinL,NMDAinL,AMPAinR,AMPAinL public GABAin objref synli...

Hi, Where s is the gating variable modeled as an instantaneus jump of magnitude 1 when a spike occours in the presynaptic neuron followed by an exponential decay with time constant of 2ms for the AMPA and 1ms for the GABAa. Sorry I missed a zero in the tau constant! GABA tau=10 msec. This is unforg...

Yes my group of research is about STPD, but we want to check if the LTP and LTD could be achieved from the biophysical point of view. So we don't do any hypotesis about the STPD shape (composed by the 2 exponetial curve or whatever you want) . We think that teh calcium dynamics and the magnesium cou...

I would to know if this procedure is correct: I have a NMDA point process or a Ca channel process and an AMPA pointprocess. The operation I want to do is: the NMDA channel or the CA channel update some internal field during the simulation time. For each simulation step I want to update the AMPA weig...

Hi, I want to implement the following postsynaptic current: Isyn=gmax*s*(V-Vsyn) Vsyn=0 for AMPA (excitatory) Vsyn=-70 mv for the GABA (inhibitory) Where s is the gating variable modeled as an instantaneus jump of magnitude 1 when a spike occours in the presynaptic neuron followed by an exponential ...

O I see, all right!

I'm importin in NEURON the morphological files from this database: http://neuromorpho.org/ In particular I'm working with the Makram pyramidal, chandelier and basket cells. The files both asc and swc are imported correctly in the Import 3D interface. After this I export them to the network builder, ...

okanerkaymaz wrote:hi, all friends
i download mr. Alain Destexhe's publication's demo file BAKCP.zip but i can't compile with NEURON 5.9 and i have errors
folowing error code in NEURON 5.9

best regard

I'm searching for the same file, anybody has the link?

I would think that an interesting rule is one for which there is experimental evidence, or at least one that could be attributed to some biologically plausible mechanism. Does this rule satisfy either of these criteria? Is there a way to calculate derivatives using the NMODL ? Not that I am aware o...

O ted that's great! It was exaclty what I wanted! I have some question about the code: when you declare the v and i in the ASSIGNED block, it means that v is the voltage corresponding to the section where the Psyn will be placed? And what about the declaration: NONSPECIFIC_CURRENT i what does it mea...

About the Iout: The Iout could be seen as the derivate of the calcium concentration. This is of course an appoximation but for beginning is more easy. About the channel activity: I mean the following equation /* * calculate the activation level of the channel * dx/dt = (activation*tau1 - x)/tau1 * x...

"All things are possible with programming." But before plunging into implementational details, some questions about your conceptual model to make sure that what you end up with is a close match to what you have in mind. The rule described in your posting is already a mix of concept and im...

Hi, I'm a genesis users and I never used neuron. I would to ask if it's possible to implement in neuron a custom learning rule for a NMDA synpase. I'm blocked with this problem in genesis for a long time, the problem is that in genesis I have to compile a library to do so, but t I'm the first user t...