Switching L2/3 morphology in model but preserving intrinsic and synaptic properties.
Posted: Fri Dec 02, 2022 12:09 am
Hello
I am using the following model by Aberra 2018 (https://senselab.med.yale.edu/modeldb/S ... del=241165). I would like to replace the L23 morphology file with my own morphology file but preserve the synaptic distribution and intrinsic properties of the cell. If I simply replace the file obviously a lot of synaptic inputs will appear to be out of range as the dendritic distribution between the two morphologies is not exactly the same. Is there an automatic way I can scale the synaptic inputs and intrinsic property distributions to the new morphology without having to manually recreate those inputs and ion channel properties?
thank you,
Alexandra
I am using the following model by Aberra 2018 (https://senselab.med.yale.edu/modeldb/S ... del=241165). I would like to replace the L23 morphology file with my own morphology file but preserve the synaptic distribution and intrinsic properties of the cell. If I simply replace the file obviously a lot of synaptic inputs will appear to be out of range as the dendritic distribution between the two morphologies is not exactly the same. Is there an automatic way I can scale the synaptic inputs and intrinsic property distributions to the new morphology without having to manually recreate those inputs and ion channel properties?
thank you,
Alexandra