CVODE. SEClamp (Single Electrode Clamp) is just an ideal voltage source in series
with a resistance, while VClamp is a model of a two electrode voltage clamp with this
Code: Select all
tau2 gain +-|\____rstim____>to cell -amp --'\/`-------|/ | |----||--- |___ __|-----/|___from cell `'`' \| tau1
If your goal is to study single electrode clamp artifacts, use SEClamp (which gives you
series resistance), or use the Linear Circuit Builder to set up a model of the actual
circuitry of a single electrode clamp (so you can specify amplifier bandwidth etc.).
Use VClamp if and only if your goal is to study instrumentation artefacts of an imperfect
two electrode clamp (is anybody still using those?).