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Multiscale modeling tutorial at CNS 2018 meeting

Posted: Fri Apr 20, 2018 11:46 am
by ted
Here's a sure cure for triskaidekaphobia!

What: a whole day tutorial on Multiscale modeling from molecular level to large network level
Organizers: Salvador Dura-Bernal (SUNY Downstate, USA), Robert McDougal (Yale University, USA) and William Lytton (SUNY Downstate, USA)
When and where: Friday, July 13, at the CNS 2018 meeting in Seattle, Washington.
More information: See description at That page also has links for how to register for the CNS meeting etc..

Re: Multiscale modeling tutorial at CNS 2018 meeting -- More details

Posted: Tue Jul 10, 2018 12:13 pm
by wwlytton
July 13, 2018 Multiscale Modeling Tutorial using NEURON
CNS*18 Meeting Seattle Washington, Allen Institute Auditorium

The tutorial will present recent advances in methodologies for simulating the electrophysiology of cells and networks in the context of lower and higher scales or organization. At the lower scale, we will describe the simulation of intracellular chemical signals including calcium in subcellular compartments (dendrites and spines), with application to understanding of synaptic plasticity and the response of neuronal dynamics to modulators. At higher scales, we consider the brain as an organ, situating neurons in a complex environment of modulators, ions, and metabolism. The NEURON simulator will be used to illustrate the interactions among these levels, using NEURON's 'rxd' reaction-diffusion module for intracellular and extracellular chemophysiology, and NetPyNE ( for managing parameters and for building complex networks of detailed cells as brain structures. We will also introduce new graphical methods (GUIs) for managing these extremely complex simulations. For more information see