Synaptic Facilitation and Depression

Moderator: wwlytton

Post Reply
jw

Synaptic Facilitation and Depression

Post by jw »

I am working on a network that involves both synpatic facilitation and depression (occurring at different synapses). Using NetCon, is there a way to program this synaptic behavior? Ultimately, one synapse becomes depressed when the rate of firing increases above a certain level while the other synapse is facilitated. Thank you.
ted
Site Admin
Posts: 5786
Joined: Wed May 18, 2005 4:50 pm
Location: Yale University School of Medicine
Contact:

Post by ted »

Put the code that governs use-dependent plasticity in the synaptic mechanism's NET_RECEIVE
block.
Use the higher order elements of the weight vector to keep track of stream-specific
information about synaptic state. For examples, see chapter 10 of The NEURON Book.
Also see these NEURON implementations of models of short-term use-dependent synapatic
plasticity:
http://senselab.med.yale.edu/modeldb/Sh ... model=3264
http://senselab.med.yale.edu/modeldb/Sh ... model=3815
Post Reply