Search found 71 matches

by menica
Fri Apr 08, 2016 9:24 am
Forum: Adding new mechanisms and functions to NEURON
Topic: different mechanisms and temperature
Replies: 6
Views: 11012

different mechanisms and temperature

Dear Ted, I have a two compartments model. In one of this compartments I inserted two temperature-dependent mechanisms: hh.mod and Na/K pump. The hh is the classical built in NEURON model. In this model the parameters are setted at 6.3 degC. The parameters of the Na/K pump model are setted at the ex...
by menica
Fri Mar 11, 2016 5:13 am
Forum: Getting started
Topic: insert a membrane mechanism at a specific simulation time
Replies: 5
Views: 7123

Re: insert a membrane mechanism at a specific simulation tim

Dear Ted,
yes I agree. I know that it is not physiological.
What do you mean with:
[/quote]use events to change the pump's rate of action?


Thanks
Best
Menica
by menica
Thu Mar 10, 2016 6:39 am
Forum: Getting started
Topic: insert a membrane mechanism at a specific simulation time
Replies: 5
Views: 7123

Re: insert a membrane mechanism at a specific simulation tim

Dear Ted, thanks for the suggestion. It works but I am afraid, as you wrote, that it could easly cause problems when insterted in a more complex model (as I am planning). I could change the pump's rate before the spike arrives, make it smaller before the spike, but also this sounds to me a trick tha...
by menica
Thu Feb 18, 2016 7:30 am
Forum: Getting started
Topic: insert a membrane mechanism at a specific simulation time
Replies: 5
Views: 7123

insert a membrane mechanism at a specific simulation time

Hi!
I would like insert the N/K pump mechanism at a fixed time. This time should be equal to the delay at which I set the IClamp.
How I could do this?


Best,
Menica
by menica
Mon Jan 11, 2016 9:14 am
Forum: Getting started
Topic: time constant
Replies: 4
Views: 6585

Re: time constant

Dear Ted,
thanks for your explanation
by menica
Fri Jan 08, 2016 6:27 am
Forum: Getting started
Topic: time constant
Replies: 4
Views: 6585

Re: time constant

I need to plot the time constants for the three gates.
For rate process time constant I mean
mtau, htau, ntau
They are GLOBAL variables in the hh.mod, so are not accessible to hoc.
How can I modify the hh.mod?
by menica
Thu Jan 07, 2016 9:31 am
Forum: Getting started
Topic: time constant
Replies: 4
Views: 6585

time constant

Hi, I would like plot the rate process time constants for the K+ activation gate and the Na+ activation and inactivation gates.
There is a easy way to do it with neuron?

thanks
Menica
by menica
Thu Dec 17, 2015 8:32 am
Forum: Adding new mechanisms and functions to NEURON
Topic: chloride channel
Replies: 2
Views: 6399

Re: chloride channel

Thanks!
by menica
Thu Dec 10, 2015 6:11 am
Forum: Adding new mechanisms and functions to NEURON
Topic: chloride channel
Replies: 2
Views: 6399

chloride channel

Hi, I need to insert a chloride leak channel (CIC-2). Where I could find this .mod mechanism implemented? I try to search on modelDB, but I found only the GABA receptors model. I would like to insert also a potassium-chloride co-transporter (KCC2) and a sodium-potassium-chloride co-transporter (NKCC...
by menica
Mon Oct 26, 2015 10:04 am
Forum: Adding new mechanisms and functions to NEURON
Topic: Understanding Na Dynamics
Replies: 7
Views: 8853

Re: Understanding Na Dynamics

Hi namisha, I have your similar problems.
How did you resolve the problem to connect the na-k pump to internal sodium concentration change?

thanks
by menica
Tue Oct 06, 2015 11:35 am
Forum: Getting started
Topic: look at the currents in the neuron connected with a ExpSyn
Replies: 1
Views: 5321

look at the currents in the neuron connected with a ExpSyn

I am starting with neuron. I am trying to make a code to connect two neurons trough an exitatory synapse and look at the Na, k and pump currents. I can visualize the na and k currents in the presynaptic neuron, but seems that the signal does not arrive to the post synaptic dendtrite. This is what i ...