Search found 8 matches

by m_nadimi
Thu Jul 04, 2024 2:33 pm
Forum: Other questions
Topic: extracellular stimulation
Replies: 12
Views: 41552

Re: extracellular stimulation

Thanks for your answer and also for your concern. I already know the mechanism: with a short pulse, there isn’t enough time for the membrane to depolarize and reach the activation threshold. However, in DBS, the intervals between pulses are also short, so each pulse effect will be accumulated, leadi...
by m_nadimi
Thu Jul 04, 2024 2:40 am
Forum: Other questions
Topic: extracellular stimulation
Replies: 12
Views: 41552

Re: extracellular stimulation

Thanks for explanation.

So in DBS, which the pulses are short, the high frequency is important to the AP generation.
by m_nadimi
Wed Jul 03, 2024 2:06 pm
Forum: Other questions
Topic: extracellular stimulation
Replies: 12
Views: 41552

Re: extracellular stimulation

My background is electrical engineering.
by m_nadimi
Wed Jul 03, 2024 11:31 am
Forum: Other questions
Topic: extracellular stimulation
Replies: 12
Views: 41552

Re: extracellular stimulation

My problem is solved. somaL and somaR were in the same locations (I missed the negative sign). I have a conceptual question (Sorry for asking a lot) By setting a pulse duration of 100 ms, I see AP generation. However, if I reduce the pulse width to 0.1 ms, APs are not generated. Is this expected beh...
by m_nadimi
Tue Jul 02, 2024 7:32 am
Forum: Other questions
Topic: extracellular stimulation
Replies: 12
Views: 41552

Re: extracellular stimulation

Thank you for your response. While checking h.psection, I found that the length was incorrect due to a misuse of pt3dadd. Initially, I was using a single coordinate for the entire section. I corrected this by using 21 points, as specified in the hoc file. However, I still do not see an action potent...
by m_nadimi
Mon Jul 01, 2024 9:43 am
Forum: Other questions
Topic: extracellular stimulation
Replies: 12
Views: 41552

Re: extracellular stimulation

Thanks for your answer. I'm starting to model simple neuron and then step by step make it more complex. Right now, I'm using the stimsphere code example. When I run the downloaded example directly as a .py file, it works fine. However, when I use the code below, it doesn't work correctly and just ou...
by m_nadimi
Wed Jun 19, 2024 10:27 am
Forum: Other questions
Topic: extracellular stimulation
Replies: 12
Views: 41552

extracellular stimulation

Good questions. Your instructor/advisor hasn't answered them, or did you ask? They usually don't bite. And if they do, shame on them. Should the extracellular potential be added to all of these compartments or just nodes of ranvier? All compartments, unless your conceptual model includes wrapping th...
by m_nadimi
Wed Feb 21, 2024 12:18 pm
Forum: ModelDB and other online sources of models
Topic: couldn't run model from modelDB
Replies: 1
Views: 50554

couldn't run model from modelDB

Hello, I'm new to NEURON and I'm trying to use this model from modelDB. https://modeldb.science/260967?tab=1 I compiled it with nrnivmodl command. and then I tried to run it with nrngui mosinit.hoc. but I get this error: na is not a MECHANISM in setparam.hoc near line 424 insert na ^ xopen("set...