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Now that I have saved a workable ses. file for a simple GUI made model, and I want to change the ena from default by changing nao and nai. would you please give a concrete example; eg,I'd like nao and nai to be 44 mM and 50 mM respectively? the Neuron Book is still a bit too abstract. Should I write...

A very basic question, which may sound silly. Now I can only do simple modeling using Neuron GUI and recreate the model by writing simple init.hoc that contains loading ses file information. I am wondering how to combine GUI with hoc programming to get more flexibility. After opening nrngui and recr...

We’d like to use a Na equilibrium potential different from the default value. Would you please give a concrete example of writing hoc commands to use the Na equilibrium potential produced by internal Na 50 mM and external Na 44 mM? I tried but always got error reminders.

1) Thanks a lot, Ted, for your great support! I tried as you said, it worked well. But, can we do it the other way round? That is, can I create the cell model first using Cell Builder and save it as ses. File, and then load it, and use it when I create channels using the Channel Builder? 2) If we ha...

Only using GUI, if I have created a cell using Cell Builder with hh Na and hh K channels. If I create another channel using Channel Builder, how can I insert this channel to that cell I have created? I mean, how can I insert the channel created by Channel Builder to the cell created by Cell Builder ...

Ted, Thank you very much for your detailed answers. They are very helpful to me. 1) By ‘capacitive transients’ I mean the electrode or membrane capacitance mediated charging/discharging currents while the clamping voltage changes in single electrode voltage clamp experiments. In real such experiment...

After adjusting the initial potential, the result looked OK with flat baseline. Now several other questions: 1) How to removed the capacitive transients in SEClamp? 2) In the Channel Builder, is there a way to change the equilibrium potential value of HH sodium currents or HH potassium currents if w...

I tried a simple SEClamp "experiment"after entering a HH Na Channel and a HH K channel in the Cell builder(instead of in the Channnel Builder).Basically, it seemed OK and the i-t curve looked like what I expected. There are two problems: 1) I used a three-epoch voltage stimulation, the fir...

I am a beginner to studying NEURON, and have just read some relevant materials online. Now my colleague has given me the list of channels existing in a species of neuron she is studying, including 9 channels (eg.A channel, Kdr channel, HCN channel, Nav, CaHVA...) with their maximal conductances, rev...