Search found 38 matches

by melissamou
Sun Jan 15, 2012 10:29 pm
Forum: Adding new mechanisms and functions to NEURON
Topic: the default value of extracellular mechanism
Replies: 1
Views: 2456

the default value of extracellular mechanism

Hi Ted, Happy new year! I have submitted a paper and now get the comment from the reviewer, there is one question about my neuron model that I do not know how to answer. Firstly, let me introduce my neuron model. The model is a myelinated axion. I use extracellular mechanism in the model, and the ex...
by melissamou
Tue Jan 04, 2011 1:10 am
Forum: Getting started
Topic: how to define temperature for each node of ranvier
Replies: 10
Views: 6523

Re: how to define temperature for each node of ranvier

Hi Ted, Do you know the whole mod file for pas? I can only find the passive.mod. The localtemp has nothing to do with pas.mod, i just want to use it as a local variable. so that i can define the localtemp for different myelin. in my code, we want to hot some myelin, so the temperature for different ...
by melissamou
Mon Jan 03, 2011 10:04 am
Forum: Getting started
Topic: how to define temperature for each node of ranvier
Replies: 10
Views: 6523

Re: how to define temperature for each node of ranvier

Hi Ted, I have searched a mod file named passive, is it the pas model for myelin? and i have changed the code in passive.mod as following TITLE passive membrane channel UNITS { (mV) = (millivolt) (mA) = (milliamp) (S) = (siemens) } NEURON { SUFFIX passive NONSPECIFIC_CURRENT i RANGE g, e, localtemp ...
by melissamou
Mon Jan 03, 2011 2:17 am
Forum: Getting started
Topic: how to define temperature for each node of ranvier
Replies: 10
Views: 6523

Re: how to define temperature for each node of ranvier

Hi Ted, Thanks so much for your full and clear explanation about how to define local temperature for hh.mod. Now i meet another question, we want to change the temperature for myelin which I define like this insert pas e_pas = -65 g_pas = 1.5e-5/diam // S/cm2 cm=0.157/(PI*diam) // uF/cm2 fac = q10^(...
by melissamou
Wed Dec 15, 2010 12:54 pm
Forum: Getting started
Topic: how to define the diameter of myelin
Replies: 2
Views: 2912

how to define the diameter of myelin

Hi Ted, I just confused about the diameter of the myelin, if we name d as diameter of the node, and D is the diameter of the fiber(include the sheath), so is the diameter of the myelin equal D or d? and somebody talks about the thickness of the myelin, what the thickness of myelin means? how does NE...
by melissamou
Fri Nov 05, 2010 7:40 am
Forum: Getting started
Topic: does the diameter of the mylined affect the fh mod?
Replies: 3
Views: 13318

Re: does the diameter of the mylined affect the fh mod?

Thanks very much for the detailed explaination. I have follow your advice and use the Iclamp as stimulation. i am sure the diameter and other geoetry is right but still the result is not exactly linear, the slope is smaller when the diameter is bigger. i found in FH channel(Frankenhaeuser - Huxley c...
by melissamou
Thu Nov 04, 2010 7:29 am
Forum: Getting started
Topic: does the diameter of the mylined affect the fh mod?
Replies: 3
Views: 13318

does the diameter of the mylined affect the fh mod?

hi, i inserted the fh.mod in my nodes, and i want to analysis the conduction speed of the action potential, according to some paper, the relation between conduction speed and the diameter of the fiber is linear. but when i increase the diameter of the fiber to more than 15um, i found the speed is sl...
by melissamou
Thu Nov 04, 2010 7:18 am
Forum: Getting started
Topic: how to define temperature for each node of ranvier
Replies: 10
Views: 6523

Re: how to define temperature for each node of ranvier

Sure,I really appreciate your help. It is my pleasure to cite NEURON. thanks.
by melissamou
Wed Nov 03, 2010 1:48 pm
Forum: Getting started
Topic: how to define temperature for each node of ranvier
Replies: 10
Views: 6523

Re: how to define temperature for each node of ranvier

Many thanks, i use fh.mod. and i have change the global celsius to locatemp according your example. and it work. thanks a lot.
by melissamou
Wed Nov 03, 2010 8:32 am
Forum: Getting started
Topic: how to define temperature for each node of ranvier
Replies: 10
Views: 6523

how to define temperature for each node of ranvier

hello Ted,

now i have 21 nodes of Ranvier in my model, i use "forall" to define the temperature, do you know how to define the temperature for one of those nodes while the temperature for the others nodes are the same?
by melissamou
Mon Nov 01, 2010 7:17 am
Forum: Getting started
Topic: what's the boundary conditon in extracellular_stim_and_rec
Replies: 4
Views: 4202

Re: what's the boundary conditon in extracellular_stim_and_rec

i would like to write my question clearly, Boundary conditions in this case refer to the conditions at the ends of a simulated neuron because i have a fibre model with a finite length. All nodes of Ranvier will use the FH equations to describe the changes in Vm(membran potential), but the end nodes ...
by melissamou
Mon Nov 01, 2010 6:51 am
Forum: Getting started
Topic: what's the boundary conditon in extracellular_stim_and_rec
Replies: 4
Views: 4202

Re: what's the boundary conditon in extracellular_stim_and_rec

Membrane potential is the difference in potential between the inside of a cell and the extracellular space immediately adjacent to the outside surface of the cell. sorry, my english is not so good, do you mean the membran potential will immediately adjacent to the outside surface of the cell or the...
by melissamou
Sun Oct 31, 2010 8:30 am
Forum: Getting started
Topic: what's the boundary conditon in extracellular_stim_and_rec
Replies: 4
Views: 4202

what's the boundary conditon in extracellular_stim_and_rec

Hi Ted, i am simulating a extracellular stimulation, the model is a myelined axon with 21 myelins and 21 nodes. The extracellular electric potential is calculated from Comsol. first i get the center coordinate of each segment for all the myelined and nodes in NEURON, this is accroding your "int...
by melissamou
Thu Oct 28, 2010 4:36 am
Forum: Getting started
Topic: HOW TO omit the start and end points in a vertor
Replies: 4
Views: 2508

Re: HOW TO omit the start and end points in a vertor

Cheers,now it work, i modify the code like this: x_model.append(xint.c(1,xint.size()-2)) y_model.append(xint.c(1,xint.size()-2)) z_model.append(xint.c(1,xint.size()-2)) the result is correct then, thank you very much.
by melissamou
Wed Oct 27, 2010 4:10 pm
Forum: The GUI
Topic: problem with save Ascii file
Replies: 1
Views: 6287

problem with save Ascii file

Hi Ted, i try to save the membrane potential of different points which is function of time to a ascii file. i click the window and then choose the print & file window manager, then select the window which including these potential lines and "print" as ascii. but i open it use wordpad, ...