www.neuron.yale.edu

Hi,

I am trying to add two mechanisms that will write ica - the sodium calcium exchanger and the long lasting calcium mechanisms to my model.

So the first part of the for the Nacax would look like:

SUFFIX naca
USEION ca READ cai,cao WRITE ica
USEION na READ nai,nao WRITE ina

and the first part of the next would be

SUFFIX caL
USEION ca READ cai,cao WRITE ica

I have read that ica is basically pooling the calcium currents together.

So does that mean that :

soma.ica=soma.i_naca+soma.i_caL ??

The reason I ask is that I tried saving ica and i_naca and i_caL separately(after running my model for about 500ms) - but adding i_naca with i_caL does not give me ica - instead the ica has a different value ??

The units for everything is mA/cm2

Please advice.

Thanks,
Meena

The only way to tell if there is even a problem is to examine and test your code. Zip up
just the minimal hoc, ses, and mod files that are sufficient to reproduce what you are
seeing, and send it to me
ted dot carnevale at yale dot edu
and I will look into the matter.

Hi Ted,

Thanks so much but I've looked and looked at it - and found that in my model -
(as mentioned I have INaca and ICal and ICap)

ica in my model was = ICal - INaca

I found this out - by removing one of the currents mech and looking at the ica and the adding the mechanism - as far as adding up goes - it does add up.

So I will not trouble you further with this....thanks so much !!!
I do appreciate your help !!

Meena