permeability, conductance
Posted: Thu Sep 21, 2006 4:55 pm
Dear Friends,
as you know for some ionic current (e.g T-current), insted of conductance,
I=Gbar_ion *m^q*h*p *(v-E_rev)
we use permebility (GHK equation.)
I=P_ion *m^q*h*p *GHK()
the unite of conductance is [ S/cm2] (simens/area) and unite of permeability is [cm/sec ] (length/time)
let me define for a special ion
G_ion [s/cm2] -------> conductance density in section A
area(cm2) -----> area of section A
P_ion [cm/sec] -------> ion permeability in section A
g [s] ---------------> conductance of one channel
then, we can calculate number of channel in section A, as follow
n= G_ion*area/g ----> number of channel
N=G_ion/g -----> channel density
right?
if yes,then what should we do if we have permeability?
Do we have the same relation?
Do we can define permeability for one channel?
as you know for some ionic current (e.g T-current), insted of conductance,
I=Gbar_ion *m^q*h*p *(v-E_rev)
we use permebility (GHK equation.)
I=P_ion *m^q*h*p *GHK()
the unite of conductance is [ S/cm2] (simens/area) and unite of permeability is [cm/sec ] (length/time)
let me define for a special ion
G_ion [s/cm2] -------> conductance density in section A
area(cm2) -----> area of section A
P_ion [cm/sec] -------> ion permeability in section A
g [s] ---------------> conductance of one channel
then, we can calculate number of channel in section A, as follow
n= G_ion*area/g ----> number of channel
N=G_ion/g -----> channel density
right?
if yes,then what should we do if we have permeability?
Do we have the same relation?
Do we can define permeability for one channel?