Extracellular make difference in synaptic input
Posted: Fri Feb 17, 2023 1:30 pm
Dear colleagues,
I used extracellular mechanism with the xtra.mod mechanism to deal with the input. I just found that when I perform the same simulation (same synapses and events) but without extracellular, I don't get the same results (particullarly it seems that the high frequency voltage stimulation due to synaptic input seems to be filtered). Is it something knew and exepected ?
Best
Edit
Found the solution on the forum (viewtopic.php?p=14585&hilit=netcon+and+ ... lar#p14585).
This is due to the fact that point processes at 0 or 1 of a section do not deliver anymore current if extracellular is inserted.
The workarround proposed by Ted (thanks for all his contributions on this forum) is the following :
I used extracellular mechanism with the xtra.mod mechanism to deal with the input. I just found that when I perform the same simulation (same synapses and events) but without extracellular, I don't get the same results (particullarly it seems that the high frequency voltage stimulation due to synaptic input seems to be filtered). Is it something knew and exepected ?
Best
Edit
Found the solution on the forum (viewtopic.php?p=14585&hilit=netcon+and+ ... lar#p14585).
This is due to the fact that point processes at 0 or 1 of a section do not deliver anymore current if extracellular is inserted.
The workarround proposed by Ted (thanks for all his contributions on this forum) is the following :
Code: Select all
seg_x = 1e-3 if seg_x==0 else seg_x=1- 1e-3 if seg_x