I'm trying to simulate the intracellular electric field gerneated by the action potential propagating along the myelinated axon with the influence of sodium ion accumulation at the Node of Ranvier.
For the uniform myelinated axon and its initialization, I used the cable.hoc and init.hoc from:
https://senselab.med.yale.edu/modeldb/S ... model=9851
Then I tried to use the nacum.mod file from:
https://senselab.med.yale.edu/modeldb/S ... 800#tabs-1
I put cable.hoc, init.hoc and nacum.mod file into another new created file called ''new model'', and use mknrndll to compile ''new model''.
- After compiling the file, it showed that nrnmech.dll was built successfully. Did that mean that the intracellular sodium ion accumulation mechanism was successfully inserted to my model?
I want to insert the sodium ion accumulation mechanism into the Node of Ranvier, what modification that I have to apply to my model?
I also wonder how to record the intracellular voltage along the axon and save it to another file which I want to use later in Matlab to plot the electric field.
Kind regard,
SUN XIAOQING