www.neuron.yale.edu

I would like to create a synaptic current (say GABAergic) that changes its maximal conductance, within a small range, each time NetStim is on. This way, the amplitude of the postsynaptic current has some variability each time the synapse is stimulated by NetStim. I have three synapses right now and I can assign each of them a random maximal conductance within a specific range but when I try to make it change as I am stimulating at 5 Hz, the values do not change. This is what I have so far that assigns the random conductance to the 3 synapses:

objref r
r=new Random()
r.uniform(0.0004, 0.0006)
for i=0,2 GABAA_S.g=r.repick()

Is there an easy way to get the synapses to repick from the range each time a presynaptic spike comes in?

Good question. Here are several working examples of synaptic mechanisms that
display trial-to-trial fluctuation:
http://www.neuron.yale.edu/phpBB2/viewt ... 08acb111d3