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Sensitivity Analysis
Posted: Fri Feb 03, 2006 2:30 pm
by mattmc88
Has anyone attempted "sensitivity analysis" on the solution of an optimization in NEURON? On a related note, has anyone computed the Hessian matrix at a solution point? Any helpful information or code related to sensitivity analysis within NEURON's MulRunFit would be much appreciated.
Thanks!
Posted: Tue Feb 07, 2006 11:41 am
by hines
The praxis (principal axis) optimizer more or less gives you a continuous indication of the shape of the bowl (quadratic form) while it is carrying out its work. See
http://www.neuron.yale.edu/neuron/stati ... val_praxis
If you click on the
MulRunFitter[0]Optimize/ PrincipalAxisVariation button a window should pop up that displays these principal axes.
I believe, though if I am incorrect someone should tell me, that the principal axes and principal values are synonymous with sensitivity in the optimization context.