multi compartment model

[thats_karlo]

Hello evrybody,

In Neuron program, when i use the following code

creat soma
soma .nseg=1
soma.L=18.8
soma.diam=18.8
soma.Ra=123.
insert hh


1-Dose it mean, i have single comartment model with one HH (Na ,K) channel ?
1-a;How should i change code to have mutli compartment modle?
1-b; How can i change number of HH (Na ,K) channel in this single compartment (if it is single!)?

2-How can i have a distribution of HH (Na ,K) channel in modle. for example i creat a 3 compartment for soma that in first comparment i have one HH (Na ,K) channel , in second 2 HH (Na ,K) channel ,and in third part 3 HH (Na ,K) channel ?


I awite for your reply. Thank you very much

Karlo

[ted]

Good questions. A good place to find the answers: go to NEURON's
Documentation page http://www.neuron.yale.edu/neuron/docs
and look under the heading
Key papers about NEURON
for this item
"The NEURON Simulation Environment"
An earlier paper with the same title, expanded from our first article in
Neural Computation. Full of useful information for NEURON newbies.

1-Dose it mean, i have single comartment model with one HH (Na ,K) channel ?

You have a section that is shaped like a fat tomato can: 18.8 diameter and length.
It has a single compartment.
Its membrane contains voltage-gated gk and gna, and an ohmic leak conductance
with the standard HH conductance densities. This corresponds to hundreds or
thousands of ion channels (offhand I don't know the unitary conductances of squid
axon channels).

1-a;How should i change code to have mutli compartment modle?

That's what the nseg parameter does. Read about it in the paper cited above.

2-How can i have a distribution of HH (Na ,K) channel in modle. for example i creat a 3 compartment for soma that in first comparment i have one HH (Na ,K) channel , in second 2 HH (Na ,K) channel ,and in third part 3 HH (Na ,K) channel ?

Read about range variables in the paper cited above.