Synaptic Facilitation and Depression
Moderator: wwlytton
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jw
Synaptic Facilitation and Depression
I am working on a network that involves both synpatic facilitation and depression (occurring at different synapses). Using NetCon, is there a way to program this synaptic behavior? Ultimately, one synapse becomes depressed when the rate of firing increases above a certain level while the other synapse is facilitated. Thank you.
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ted
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Put the code that governs use-dependent plasticity in the synaptic mechanism's NET_RECEIVE
block.
Use the higher order elements of the weight vector to keep track of stream-specific
information about synaptic state. For examples, see chapter 10 of The NEURON Book.
Also see these NEURON implementations of models of short-term use-dependent synapatic
plasticity:
http://senselab.med.yale.edu/modeldb/Sh ... model=3264
http://senselab.med.yale.edu/modeldb/Sh ... model=3815
block.
Use the higher order elements of the weight vector to keep track of stream-specific
information about synaptic state. For examples, see chapter 10 of The NEURON Book.
Also see these NEURON implementations of models of short-term use-dependent synapatic
plasticity:
http://senselab.med.yale.edu/modeldb/Sh ... model=3264
http://senselab.med.yale.edu/modeldb/Sh ... model=3815