rookie - quick question - membrane potential set

[benjamingrantdu]

Sorry I did the tutorial but never found the variable for resting potential, how can you set the rest potential to zero? Thank you
Ben

[ted]

the tutorial

There are lots of tutorials. Which one do you mean?

[benjamingrantdu]

http://www.anc.ed.ac.uk/school/neuron/

but if you could help me with my current question rather than my tutorial selection it'd be really helpful

[ted]

Presumably the cells in that tutorial have multiple ion channels, each with its own ionic selectivity and voltage-dependent gating. To make resting potential 0 it is necessary to determine the "original" resting potential, then shift all ionic equilibrium potentials and voltage-dependent gating by that amount. Offhand I can't imagine why anyone would want to do such a thing. If the aim is to see membrane potential deflections relative to rest, why not just subtract resting potential from the recorded voltages?

[benjamingrantdu]

i just had to model something with v_rest = 0 for a homework assignment, I understand that it is easy to adjust the rest potential. The cells we had weren't HH modeled(no ions channels used, just used subthreshold stimulation) but yeah agreed it was not particularly necessary. But anyway, thanks. i just set intial V = 0 and e_pas = 0 and all was golden
Ben