'connect' function in NEURON

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mganguly
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'connect' function in NEURON

Post by mganguly »

Hi

I am curious to know how does the 'connect' function in neuron work ? How does it account for changes if there are two different mechanisms inserted at either end of the junction between the two sections ( or when there are different parameters assigned eg, gKmax, temperature etc)

Thanks,

Mohit
ted
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Re: 'connect' function in NEURON

Post by ted »

connect affects the electrical boundary conditions of the two sections that are connected, at the point at which they are connected.

celsius is "global" in the sense that all sections will have the same value of celsius; there is no variable called "temperature." If you need to represent spatially inhomogeneous temperature in your model, the NMODL code for each temperature-sensitive mechanism must have its own range variable for temperature that you can call whatever you like, as long as it's not a reserved name. To be perfectly consistent, each mechanism should also use that temperature parameter to compute its own ionic equilibrium potentials--and that also applies to any mechanism that involves a NONSPECIFIC_CURRENT.

Any parameter that is a RANGE variable can be spatially inhomogeneous.
mganguly
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Joined: Sun May 03, 2015 7:05 pm

Re: 'connect' function in NEURON

Post by mganguly »

Hi,

I was recently thinking about it again. In what way does the connect affects the electrical boundary between the two sections ?

Mohit
ted
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Re: 'connect' function in NEURON

Post by ted »

1. Conservation of charge (sum all axial currents at the point of attachment is 0).
2. At the point of attachment, the potential at the parent node is equal to the potential at the child node.
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