Mechanosensitive channels

NMODL and the Channel Builder.
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Mechanosensitive channels

Post by afc » Thu Sep 29, 2016 7:50 am

Dear all,

I was wondering if there is a turn around in NEURON, i.e, a complementary software or an extension of NEURON itself, that enables the embedding of a neuron in a physical space, allowing the studying of mechanosensitive channels?

Thank you all in advance!

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Re: Mechanosensitive channels

Post by ted » Thu Sep 29, 2016 11:48 am

No, but if you can tell me a mathematical description of how force or deformation affects the channels, I can tell you how that can be implemented with some combination of (hoc and/or Python) and (NMODL or a ChannelBuilder).

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