HH channel and negative inject current

The basics of how to develop, test, and use models.
Post Reply
Posts: 34
Joined: Tue Aug 23, 2005 10:07 am

HH channel and negative inject current

Post by reza_rzm »

Dear Freinds,

In toturial Neuron file, sThA.hoc is a code for a simple soma with HH channel ,that we inject current (IClamp) in soma. for a current with amp=0.1 i see a train of spikes durring the current injection.

But, for amp=-0.1 again i see one spike in end of pulse,!!!!

this spike is similar to low thershold Ca spike that we see in another cod of tutorial sThD.hoc . in this code we insert CaT channel in soma as well as HH channel.

i guess it should be some misudrestanding. from HH model?

or is it somthing else in Neuron?

I await for your reply! Thank's in advance
Site Admin
Posts: 5784
Joined: Wed May 18, 2005 4:50 pm
Location: Yale University School of Medicine

rebound spike, or anode break excitation

Post by ted »

Without playing with the model you mention, my guess is that you are seeing
something that is called rebound spiking, or anode break excitation. This is an
interesting property of many kinds of excitable tissue, and you will find it described
and explained in standard neuroscience textbooks. You might also try googling
any of these phrases or their variants:
rebound spike (or rebound spiking)
rebound excitation
anode break
Post Reply