Is there any network model using extracellular mechanism in simulating DBS

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breakwave922
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Is there any network model using extracellular mechanism in simulating DBS

Post by breakwave922 » Wed Feb 06, 2019 5:49 pm

I plan to implement deep brain stimulation (DBS) to a network model I’m working with. I’m wondering if there is any network level computational study with DBS.
I noticed that some models used intracellular current injection to approximate the DBS. But I want to model it using extracellular induced field which would be more realistic when axonal projection across regions is involved in the model. I found a good survey paper about electrostimulation in different models. https://iopscience.iop.org/article/10.1 ... /4346/meta.
Yet, I haven't found a network model doing DBS so far. It would be helpful if there is some established method as reference to my research.
Appreciate if anyone can help me to find it.

ted
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Re: Is there any network model using extracellular mechanism in simulating DBS

Post by ted » Wed Feb 06, 2019 10:31 pm

I am not aware of any published modeling studies of extracellular stimulation of networks in which the target of the simulation was a network model. That doesn't mean that no such papers exist.

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