## Coupling conductance Pinsky & Rinzel (1999)

Moderator: wwlytton

pdennevis
Posts: 3
Joined: Fri Dec 09, 2016 10:37 am

### Coupling conductance Pinsky & Rinzel (1999)

Dear all,

Reading Pinsky and Rinzel (1999) about a model of a pyramidal neuron, I stumbled upon the following. They have developed a twocompartmental model in which the currents are normalized per unit surface area. The two compartments are coupled, and current is allowed to flow between compartments by a coupling conductance gc.

In the paper, the resistance between the two compartments is calculated as the axonal resistance of half of the first compartment plus the axonal resistance of half the second compartment, which are both cylinders. I understand that this is the same as calculating the axonal resistance of half of the total cylinder (compartment 1 + 2).

To calculate the conductance between two compartments per unit area, they use the constants provided in Traub(1991). I looked them up and calculated the conductance myself, but I ended up with a value in the range of 10^-10 S/um^2. Can someone tell me what went wrong?

r=[4.23; 2.89; 2.42] %um
l=[125; 120; 110] %um
Ri=100e4; %Ohm um
gc=r./(Ri.*l.*l);
gc=sum(gc) %S/um^2

Pinsky & Rinzel (1999)

Traub(1991)

Traub(1991)

ted