Search found 6300 matches

by ted
Wed Apr 12, 2006 10:55 am
Forum: Adding new mechanisms and functions to NEURON
Topic: Na and persistent NaP channel
Replies: 5
Views: 6264

You're quite welcome. Sooner or later, you probably would have figured this out
on your own anyway.
by ted
Tue Apr 11, 2006 8:10 pm
Forum: Other questions
Topic: Firing threshold calculation
Replies: 1
Views: 4765

How to find spike threshold automatically

nrn/lib/hoc/thresh.hoc implements a binary search that can be quite useful for finding spike threhold. Read the source code to understand the details, but basically it adjusts a user-specified variable and uses an APCount to detect the spike. Here's an example of its use: 1. Create a file that conta...
by ted
Tue Apr 11, 2006 9:36 am
Forum: Adding new mechanisms and functions to NEURON
Topic: Na and persistent NaP channel
Replies: 5
Views: 6264

Re: A beginner follow-up question

I'm trying to plot the individual contributions of an hh channel model and an m-current channel to the total k current vs time. For the 19th PY cell, using the Plot what? tool, the total k current might be "PY[14].soma[0].ik(0.5)." True. Assuming that the suffix for the NMODL M-current ch...
by ted
Mon Apr 10, 2006 9:48 am
Forum: MSWin
Topic: CPU usage while running a simulation
Replies: 10
Views: 21669

CPU usage (as reported by the Task Manager) never gets higher than 55-60%. NEURON isn't the only program that is running. What else is Windows doing? If you want the CPU to spend more time on a particular program, you have to increase that program's priority. Presumably Windows allows you to specif...
by ted
Sun Apr 09, 2006 6:56 pm
Forum: Getting started
Topic: number of channel
Replies: 3
Views: 4588

Permeability of a patch of membrane is the product of the membrane area, channel density,
and permeability of a single channel. Channel density and single channel permeability can
be collapsed into a single value which has units of "permeability density", i.e.
permeability/area.
by ted
Fri Apr 07, 2006 11:06 am
Forum: Getting started
Topic: number of channel
Replies: 3
Views: 4588

Conductance density is in units of conductance/area, so total conductance is the product of area and conductance density. To find the number of channels required to produce that total conductance, divide total conductance by the conductance per channel. The arithmetic is similar if you are dealing w...
by ted
Fri Apr 07, 2006 10:58 am
Forum: From Computer to Brain
Topic: Source code and errata for FCTB
Replies: 0
Views: 84510

Source code and errata for FCTB

I should point out that Bill Lytton has posted the source code for the models and exercises
in his book "From Computer to Brain" on NEURON's WWW site--see
http://www.neuron.yale.edu/fctb/
A pdf that contains a list of errata is also downloadable from that URL.
by ted
Fri Apr 07, 2006 10:54 am
Forum: General questions and discussions about computational neuroscience
Topic: How to start with neural computation
Replies: 1
Views: 5212

"Neural computation" covers a wide range of activities. At one extreme are people who spend all their time working on theory that draws a few inspirations from experimental neuroscience. At the other extreme are experimentalists who use computational modeling as just another research tool,...
by ted
Thu Apr 06, 2006 1:29 pm
Forum: Adding new mechanisms and functions to NEURON
Topic: ion valence must be defined in the USEION statement
Replies: 1
Views: 3506

There are several errors in the USEION statement, but It's not clear to me why you are bothering with a USEION statement at all. Is your model going to include an accumulation mechanism for this new ionic species? Are there other mechanisms that will affect, or be affected by, the concentration or e...
by ted
Thu Apr 06, 2006 1:01 pm
Forum: NEURON Announcements
Topic: 2006 NEURON Simulator Meeting
Replies: 4
Views: 14599

talks and tutorials at the NEURON Simulator Meeting

The agenda for the 2006 NEURON Simulator Meeting continues to grow. Here are three more reasons to join us at UT Austin, May 5-7-- Discussion: "NEURON: quo vadis?" Moderator: Michael Hines The agenda is to discuss future directions for NEURON, in order to help it continue to evolve to meet...
by ted
Thu Apr 06, 2006 1:01 pm
Forum: NEURON Announcements
Topic: 2006 NEURON Simulator Meeting
Replies: 4
Views: 14599

Parallel network simulations at the NEURON Simulator Meeting

The registration deadline (April 21) for the 2006 NEURON Simulator Meeting is rapidly approaching! For more information see http://www.utexas.edu/neuroscience/NEURON2006/nsm2006.html One of the featured speakers is Michael Hines, who will present a tutorial and run a workshop on using NEURON to impl...
by ted
Wed Apr 05, 2006 6:17 pm
Forum: Other questions
Topic: NEURON exited abnormally
Replies: 4
Views: 4829

Is a java runtime machine neccessary for loading the nrnmech.dll?
No.
Additionally i have to say that the java runtime environment doesn't work correctly on my computer
Do you need to use Java? Nothing in NEURON requires Java.
by ted
Wed Apr 05, 2006 1:02 pm
Forum: Optimization
Topic: MultupleRunFitter[0]Generators output differs from sims
Replies: 2
Views: 6278

Actually the false assumption was that the MRF's generator was plotting the full time course of the fitted variable. The simulated "variable to fit" is captured with Vector.record. After a run, this recording is interpolated to find the values of the "variable to fit" at the same...
by ted
Wed Apr 05, 2006 12:54 pm
Forum: Other questions
Topic: NEURON exited abnormally
Replies: 4
Views: 4829

Have you tried deleting nrnmech.dll and running mknrndll again?
by ted
Tue Apr 04, 2006 8:21 pm
Forum: Anatomically detailed models
Topic: 3D points of a segment
Replies: 1
Views: 4600

Re: 3D points of a segment

Does point (x1,y1,z1) correspond to the "0" end of the segment and (x10,y10,z10) correspond to the "1" end of the segment? First a word about terminology. Segments do not have 0 or 1 ends. In your code example, a is a section, and its 0 and 1 ends are at x1,y1,z1 and x10,y10,z10...