Search found 21 matches

by Tuoma
Wed Aug 30, 2023 5:02 pm
Forum: Reaction-diffusion in NEURON
Topic: MultiCompartmentReaction across sections
Replies: 6
Views: 13381

Re: MultiCompartmentReaction across sections

Thanks, with 8.2.2 I always get past the init() without segfault. However, when I stop the simulation with CTR+C I always get a segfault. That wouldn't necessarily be a problem if my simulations always finished. It seems the simulation is very sensitive to the NTdiffusion value, which is expected I ...
by Tuoma
Tue Aug 29, 2023 6:47 am
Forum: Other questions
Topic: Analyzing pointers
Replies: 1
Views: 11407

Analyzing pointers

I have a list of pointers, in my case I get them from myvec = [x._ref_concentration for x in mySpecies.nodes] When I write "print(myvec[0])" I get "<pointer to hoc scalar 0>", but I'd like to know more about it and I don't know how. Is there a way to know what are the addresses t...
by Tuoma
Fri Aug 25, 2023 5:20 pm
Forum: Reaction-diffusion in NEURON
Topic: MultiCompartmentReaction across sections
Replies: 6
Views: 13381

Re: MultiCompartmentReaction across sections

I'm getting some Segmentation fault errors after using the node.include_flux in a bit longer script that simulates a number of presynaptic spines and postsynaptic sections and random connections between them. This may be a technical issue somewhere else in my code but I haven't found the cause despi...
by Tuoma
Wed Aug 16, 2023 7:15 am
Forum: Reaction-diffusion in NEURON
Topic: MultiCompartmentReaction across sections
Replies: 6
Views: 13381

Re: MultiCompartmentReaction across sections

Thanks, that seems to work.
by Tuoma
Tue Aug 15, 2023 7:11 am
Forum: Reaction-diffusion in NEURON
Topic: MultiCompartmentReaction across sections
Replies: 6
Views: 13381

MultiCompartmentReaction across sections

Is it possible to make a MultiCompartmentReaction that involves species in non-connected sections? I get an error "RxDException: Multicompartment reactions the membrane and sources and destinations must share common sections." which suggests this is not possible. Here's a MWE where I would...
by Tuoma
Thu Aug 03, 2023 6:10 am
Forum: Reaction-diffusion in NEURON
Topic: Integrating RxD Ca reactions with MOD mechanisms
Replies: 5
Views: 12345

Re: Integrating RxD Ca reactions with MOD mechanisms

Thanks to both of you - yes probably better to convert the CaDynamics_E2 mechanism to RxD to avoid conflicting cai update. I'm using NEURON 7.8.2.
by Tuoma
Tue Aug 01, 2023 4:55 pm
Forum: Reaction-diffusion in NEURON
Topic: Integrating RxD Ca reactions with MOD mechanisms
Replies: 5
Views: 12345

Re: Integrating RxD Ca reactions with MOD mechanisms

Thanks, changing the compartment size and making the clamp stimulus longer indeed solved part of the problem (previously the Ca flux through the RxD rate input was very large compared to the Ca flux through the N-type channels). So now I see that both Ca fluxes contribute to cai. However, I'm puzzle...
by Tuoma
Tue Aug 01, 2023 9:30 am
Forum: Reaction-diffusion in NEURON
Topic: Integrating RxD Ca reactions with MOD mechanisms
Replies: 5
Views: 12345

Integrating RxD Ca reactions with MOD mechanisms

I'm trying to have both MOD mechanisms and RxD reactions affect my calcium concentrations. Based on previous examples this seems to be possible but I haven't got it to work properly. Here's a MWE: from pylab import * from neuron import h,rxd h(""" load_file("stdlib.hoc") loa...
by Tuoma
Thu Oct 13, 2022 2:16 am
Forum: Reaction-diffusion in NEURON
Topic: parameter controlling the rate of influx of a species in multiple compartments
Replies: 1
Views: 11610

Re: parameter controlling the rate of influx of a species in multiple compartments

I think I resolved the issue. The problem seems to be that I first defined a "master" RxD region 'cyt' and then for each of the sections (already included in 'cyt') a separate miniregion cyts , and maybe that's what caused the error message "Rates and Reactions with species defined on...
by Tuoma
Wed Oct 05, 2022 11:09 am
Forum: Reaction-diffusion in NEURON
Topic: parameter controlling the rate of influx of a species in multiple compartments
Replies: 1
Views: 11610

parameter controlling the rate of influx of a species in multiple compartments

I'm trying to introduce RxD species and reactions into a set of compartments in a multicompartmental neuron model and give inputs to some of the species. I have a list of sections for which I'm creating the Rxd Region (after defining a cell model L5PC, in this case a regular Hay model) as seclist = ...
by Tuoma
Mon Sep 19, 2022 7:33 am
Forum: Reaction-diffusion in NEURON
Topic: Reading species concentration in a MOD file using a list of species
Replies: 1
Views: 10844

Reading species concentration in a MOD file using a list of species

I'm trying to make a .mod ion-channel mechanism file where the maximal conductance of the channel would depend on the concentration of a certain species. Currently all my molecular species are part of a list, meaning that they are called 'specs[0]' ... 'specs[19]' and I define my reactions as e.g. r...
by Tuoma
Mon Mar 01, 2021 4:18 am
Forum: Reaction-diffusion in NEURON
Topic: Running pde solver more than once
Replies: 6
Views: 20916

Re: Running pde solver more than once

I've got another issue related to this topic. I used to run my simulator from the command line (even inside a python script) to make sure there are no issues with reinitialization of the RxD model. Now I'm trying to rewrite the code to be run as a normal python function to avoid i/o overload on the ...
by Tuoma
Wed Aug 14, 2019 5:14 am
Forum: Reaction-diffusion in NEURON
Topic: decay reactions
Replies: 1
Views: 7615

decay reactions

How to implement a decay reaction (a reaction with no products)?

In an earlier NEURON version it was possible to write

Code: Select all

reaction_decay = rxd.Reaction(Ca > 0*Ca, 1e-8)
but now (v. 7.7) I get an error "AttributeError: 'Reaction' object has no attribute '_react_regions'"
by Tuoma
Fri Nov 16, 2018 6:07 am
Forum: Reaction-diffusion in NEURON
Topic: maximum length for the name of a species?
Replies: 2
Views: 3684

Re: maximum length for the name of a species?

Thanks for the reply. However, the problem persists even if I remove "nrn_region='i'", or change it to None or 'o'.
by Tuoma
Wed Nov 14, 2018 10:59 am
Forum: Reaction-diffusion in NEURON
Topic: maximum length for the name of a species?
Replies: 2
Views: 3684

maximum length for the name of a species?

I get a weird "Abort trap: 6" error that seems to depend on the length of the names of my species. MWE: from neuron import h, rxd from pylab import * h.load_file('stdrun.hoc') dend = h.Section(name='dend') cyt = rxd.Region([dend], name='cyt', nrn_region='i') specNameLen=21 specs = [] vecs ...