Search found 7 matches

by vogdb
Mon Oct 23, 2017 10:47 am
Forum: Getting started
Topic: Please recommend a book about simplification of detailed neuron models for the simulation of large networks
Replies: 4
Views: 8092

Re: Please recommend a book about simplification of detailed neuron models for the simulation of large networks

Thank you so much! I completely agree with you about conceptual model. The funny thing is that I chose an example of "rate vs spike timing" randomly and I am more interested in other things: 1. How to collapse a huge compartmental model into a IAF-like neuron. 2. What to do with multiples channels d...
by vogdb
Thu Oct 19, 2017 11:50 am
Forum: Getting started
Topic: Please recommend a book about simplification of detailed neuron models for the simulation of large networks
Replies: 4
Views: 8092

Please recommend a book about simplification of detailed neuron models for the simulation of large networks

Hi! I'm a beginner in this field. Can you please suggest a good book that explains and shows on examples how to simplify detailed neuron models for using in large networks? I have some questions, which I would be glad to be answered. - What type of neuron is better to pick? Integrate-And-Fire? Rate-...
by vogdb
Wed Sep 06, 2017 11:13 am
Forum: Reaction-diffusion in NEURON
Topic: Is there a model that handles Signaling Pathways in rxd?
Replies: 1
Views: 6459

Is there a model that handles Signaling Pathways in rxd?

I'm trying to find an example that shows usage of RxD for signaling pathways like Glu + mGluR <-> Glu_mGluR Glu_mGlur + G <-> Glu_G_mGluR ... I found some good examples in NModl like here https://senselab.med.yale.edu/ModelDB/ShowModel.cshtml?model=185858&file=/CaHDemo/mglur.mod#tabs-2 but I'm curio...
by vogdb
Tue Sep 05, 2017 10:47 am
Forum: Suggestions and Feedback
Topic: Site docu bug. Mathjax can't be loaded at RXD tutorials.
Replies: 1
Views: 10795

Site docu bug. Mathjax can't be loaded at RXD tutorials.

Sorry to post it here. I couldn't find a more proper place. Mathjax library can't be loaded and all formulas are displayed as plain Tex. Blocked loading mixed active content “http://cdn.mathjax.org/mathjax/latest/MathJax.js?config=TeX-AMS-MML_HTMLorMML”[Learn More] tut_cawave.html Loading failed for...
by vogdb
Mon Aug 21, 2017 5:59 am
Forum: Getting started
Topic: Minor capacitive current during IClamp simulation
Replies: 3
Views: 5256

Re: Minor capacitive current during IClamp simulation

Sorry for the late response. I forgot to turn on notifications. I don't see the problem. When the IClamp generates a nonzero current, soma.i_cap(0.5) is nonzero. In both cases, the value of soma.i_cap(0.5) is what Kirchhoff's current law predicts that it must be. I agree totally but I don't understa...
by vogdb
Fri Aug 18, 2017 6:38 am
Forum: Getting started
Topic: Minor capacitive current during IClamp simulation
Replies: 3
Views: 5256

Minor capacitive current during IClamp simulation

Simple soma-only that does not have any current mechanism except the capacitive one. create soma access soma objref stim soma stim = new IClamp(0.5) stim.amp = 1 stim.del = 50 stim.dur = 200 tstop = 300 During the injection the capacitive current is constant and equals a minor value 6.3e-04 micro A ...