Search found 6 matches

by gary
Fri May 03, 2013 11:48 am
Forum: NEURON + Python
Topic: Measurement of electronic distances.
Replies: 3
Views: 2764

Re: Measurement of electronic distances.

Thanks for an incredibly swift answer! (makes sense, right?) I *think* so. You can score my responses to your reply as to whether or not I really do understand! The voltage transfer ratio is voltage downstream / voltage upstream and is always <= 1. If this refers to Impedance.ratio(x) - I interpret ...
by gary
Fri May 03, 2013 11:16 am
Forum: NEURON + Python
Topic: Measurement of electronic distances.
Replies: 3
Views: 2764

Measurement of electronic distances.

Apologies in advance for another obtuse question. I enjoyed working through the electronic analysis tutorial at http://www.neuron.yale.edu/neuron/static/courses/2008/course/zclass/zclass.htm using the NEURON GUI. Returning to my Python code, I am attempting to perform a similar analysis however I ca...
by gary
Tue Jan 29, 2013 5:28 am
Forum: NEURON + Python
Topic: Recording changes in Impedance in NEURON (Python)
Replies: 14
Views: 11869

Re: Recording changes in Impedance in NEURON (Python)

If the perturbations are simultaneous, just activate all of them and then calculate whatever input impedances you need. If your model has voltage-gated channels, be sure to execute compute with the 2nd argument == 1 so that it performs the extended impedance calculation, which includes the effect o...
by gary
Mon Jan 28, 2013 9:18 am
Forum: NEURON + Python
Topic: Recording changes in Impedance in NEURON (Python)
Replies: 14
Views: 11869

Re: Recording changes in Impedance in NEURON (Python)

Thanks again for your helpful suggestions, which I am presently trying to implement! I'm hoping to investigate the effects of conductance changes, occurring at a handful of synchronous synaptic inputs onto dendrites of a cell with an input resistance of ~20 Mohm and capacitance ~300 pF, on the input...
by gary
Fri Jan 25, 2013 7:32 am
Forum: NEURON + Python
Topic: Recording changes in Impedance in NEURON (Python)
Replies: 14
Views: 11869

Re: Recording changes in Impedance in NEURON (Python)

Thanks Ted for a swift, clear, and comprehensive response. With regards to the caveats, it is reassuring to know that our assumptions of linearity and stationarity are supported by small changes in V/I amplitude with frequencies of interest that are certainly greater than the those associated with t...
by gary
Thu Jan 24, 2013 12:15 pm
Forum: NEURON + Python
Topic: Recording changes in Impedance in NEURON (Python)
Replies: 14
Views: 11869

Recording changes in Impedance in NEURON (Python)

Hello, I'm using the Python version of NEURON in attempt to model the transfer/input impedance at one location with respect to conductance changes at another at different instances during the course of a synaptic event. I've a simplified soma + 2 dendritic sections (i.e. o--) illustrated below: from...