Hodgkin - Huxley axon

Physical System

From http://www.mbl.edu

Model

Hodgkin-Huxley cable equations

Simulation

Representation

	create axon
	axon {
		nseg = 50
		diam = 100
		L = 20000
		insert hh
	}

Using the Representation

Run NEURON with above spec.

Exercises

1) Stimulate with current pulse and see a propagated action potential.

The basic tools you'll need from the NEURONMainPanel :
PointProcesses/Manager/PointManager to specify stimulation
NewGraph/ShapePlot to create graphs of v vs x and v vs t.
RunControl to run the simulation

2) Change excitability by adjusting sodium channel density.

Tool needed:
DistributedMechanisms/Viewers/ShapeName

3) Use two current electrodes to stimulate both ends at the same time.

4) Change nseg to 10.

Help reference


NEURON summer course
Copyright © 1998, 1999 by N.T. Carnevale and M.L. Hines, all rights reserved.