The code in ModelDB entry 9851 was written by Michael Hines to reproduce the results presented in the paper Moore et. al 1978. That model was developed for the purpose of examining the effects of axon geometry on spike propagation. It should not be interpreted as being a model of a particular axon from a particular organism. The model's anatomical and biophysical properties are suitable for studies of excitation and conduction from the theoretical perspective taken by Moore et al., but axons from other organisms will have properties that are at least quantitatively different, and in the case of ion channnels may also have important qualitative differences.demar wrote:I would like a point of view about this model:
. . .
It describes uniform myelinated fiber.
Is it accurate for bigger fiber, with diameter around 100 um and so internode distance around 1 cm?
By "the model" you mean something that your hoc code creates? What is your hoc code that specifies the anatomical and biophysical properties of your model?demar wrote:on the model, the threshold is highter for the smaller fiber (30 um) than for the bigger (80 um).
Not sure what this means.I'm trying to add diameter dependencies on the axon properties (cm, Ra and g_pas)
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