Search found 18 matches

by NeuroRhythms
Tue Aug 14, 2012 6:54 pm
Forum: Adding new mechanisms and functions to NEURON
Topic: Calcium current through NMDA receptor
Replies: 14
Views: 12058

Re: Calcium current through NMDA receptor

my original wording was imprecise. "permeability of Ca is 10% the total conductance flowing through a channel?" there is no conductance flow, that should really read, "is it valid to simply say that since 10% of the current is Ca++ then permeability of Ca++ is 10 percent the conductan...
by NeuroRhythms
Tue Aug 14, 2012 6:40 pm
Forum: Adding new mechanisms and functions to NEURON
Topic: Calcium current through NMDA receptor
Replies: 14
Views: 12058

Re: Calcium current through NMDA receptor

I am just looking at units in the .mod file. How can you take a microS value, place it in the GHK equation where a current value should be and get a permeability value?
by NeuroRhythms
Tue Aug 14, 2012 5:26 pm
Forum: Adding new mechanisms and functions to NEURON
Topic: Calcium current through NMDA receptor
Replies: 14
Views: 12058

Re: Calcium current through NMDA receptor

So if we know from experimental work that the Ca++ current flowing through the NMDA receptor is 10% of the total current, is it safe/scientifically valid to make the claim that the permeability of Ca is 10% the total conductance flowing through a channel? Immediately I'd think not, but this has been...