Search found 11 matches
- Mon May 02, 2016 8:22 am
- Forum: Other questions
- Topic: Help varying membrane voltage fluxuation
- Replies: 4
- Views: 2583
Re: Help varying membrane voltage fluxuation
First, thank you for your search for the figure. I apologize for providing an incorrect reference. After weeks of trying and reading, I have finally fluctuated the SD of the membrane voltage by reduce the total number of excitatory and inhibitory synapses (~900/300). In my original code, I used a se...
- Thu Apr 14, 2016 11:38 pm
- Forum: Other questions
- Topic: Help varying membrane voltage fluxuation
- Replies: 4
- Views: 2583
Help varying membrane voltage fluxuation
I am trying to reproduce some of the results of Alain Destexhe in his paper "High-Conductance State of Neocortical Neurons In Vivo (image below), in particular Fig. C1)." If I am trying to vary the membrane voltage fluctuation (SD = ~4 mV) of my system, what parameters would I theoreticall...
- Sat Apr 09, 2016 10:08 pm
- Forum: Getting started
- Topic: Adding Synapses to Pre-existing model
- Replies: 8
- Views: 9172
Re: Adding Synapses to Pre-existing model
Thanks for all of the clarification of the initialization, spacial discretion, and checking the morphological data! I understand better now and have made the appropriate changes. In particular, you explanation for the NetCon list makes a lot of sense. I was dumb to assume that NEURON would just keep...
- Wed Apr 06, 2016 12:57 am
- Forum: Getting started
- Topic: Adding Synapses to Pre-existing model
- Replies: 8
- Views: 9172
Re: Adding Synapses to Pre-existing model
Sorry, but another quick question... I would like the excitatory synapses to have excitatory quantal conductances of 1 nS. Is there a parameter I could easily change in Exp2Syn to achieve this? I thought about changing the synaptic current (syn.i) to 1 nA, but I know this is insufficient in changing...
- Wed Apr 06, 2016 12:12 am
- Forum: Getting started
- Topic: Adding Synapses to Pre-existing model
- Replies: 8
- Views: 9172
Re: Adding Synapses to Pre-existing model
Thanks for the great insight Ted. For the initialization I think I will try to use GUI's VariableStepControl tool to initialize the model to steady state at the beginning! I have been reading up on the GUI and I believe by loading the parameters the GUI outputs from the ses file, it should be suffic...
- Sun Apr 03, 2016 8:58 pm
- Forum: Getting started
- Topic: Adding Synapses to Pre-existing model
- Replies: 8
- Views: 9172
Re: Adding Synapses to Pre-existing model
Dear Ted, thank you for your quick and detailed response! It has been very helpful into guiding me in the right direction. It is unfortunate that modelDB is not working, so would you like me to send you the zip file that contains my code as well as the original code for the modelDB file I am using? ...
- Fri Apr 01, 2016 10:26 am
- Forum: Getting started
- Topic: Adding Synapses to Pre-existing model
- Replies: 8
- Views: 9172
Adding Synapses to Pre-existing model
Dear Ted, Thank you for all of our previous interactions. II have been working with NEURON for the past couple of weeks and I fainlly feel I am now somewhat competent after reading and testing my understanding of what NEURON can do. My current goal is to successfully add X number of excitatory synap...
- Thu Mar 10, 2016 1:52 am
- Forum: Getting started
- Topic: Adding Synapses (Excitatory and Inhibatory) - Staring Help
- Replies: 3
- Views: 7632
Re: Adding Synapses (Excitatory and Inhibatory) - Staring He
Thanks for your suggestion Ted! I have been reading and using the AlphaSynapse built in function in NEURON and was wondering a question. Can you put multiple AlphaSynapses in a cell model and have then both fire at different times? I have used a simple model with soma, dend[2], and an axon. I placed...
- Fri Feb 26, 2016 3:47 am
- Forum: Getting started
- Topic: Adding Synapses (Excitatory and Inhibatory) - Staring Help
- Replies: 3
- Views: 7632
Adding Synapses (Excitatory and Inhibatory) - Staring Help
Hey guys, I'm trying to understand how to add excitatory and inhibitory synapses to a simple cell and have been reading a lot of things online. I'm not really sure where to start, and I was wondering if anyone could point me in the right direction? I know in order to add these synapses, you have to ...
- Thu Jan 28, 2016 2:47 am
- Forum: Getting started
- Topic: Implementing a CHIRP stim and recording the soma
- Replies: 3
- Views: 6939
Re: Implementing a CHIRP stim and recording the soma
Thanks so much Ted! I've read both links as well as messed with more NUERON coding, testing my understanding of how the language works. In regards to the second link you provided, I had a question about the outline of a program you were discussing. Corinne tried to write "a program that determi...
- Fri Jan 15, 2016 2:15 am
- Forum: Getting started
- Topic: Implementing a CHIRP stim and recording the soma
- Replies: 3
- Views: 6939
Implementing a CHIRP stim and recording the soma
Hello all, My ultimate first goal is to implement a CHIRP stimulus into this model (https://senselab.med.yale.edu/modeldb/showModel.cshtml?model=139653) at various points and record the neuron at different points. This information will be then used to find the resonance of this model. I have been wo...